Pre-Clinical Scientist III (PhD level)- Organic Chemist- Cambridge, MA Cambridge, Massachusetts

Orbis Clinical is seeking a Scientist III – Organic Chemist located in Cambridge, MA for 6 months.

Job Title: Scientist III – Organic Chemist

Location: Cambridge, MA

Initial contract: ~6-months (approved thru the end of 2026) likely to extend for longer 

Job Description

Company is one of the world’s leading biopharmaceutical companies, with a focus on developing therapies for serious neurologic diseases. We are committed to research that uncovers the underlying biology of complex diseases. The medicinal chemistry group at company is seeking a creative and self-motivated organic chemist to design, develop, and apply existing and new technologies to antibody-oligonucleotide conjugate drug discovery. The position is designed to provide a unique opportunity for scientists to gain exposure to drug discovery & development and train in an industry research setting. In this role, you will collaborate with cross-function teams and leverage your strong chemistry background to synthesize oligonucleotide conjugates and support various company programs. 

What You’ll Do

• You will be joining the medicinal chemistry team at company, and work in a cross-functional and multidisciplinary environment to support our antibody-oligonucleotide conjugate platform. 
• As part of the medicinal chemistry effort, you will use your strong chemistry background to design, synthesize and purify functionalized oligonucleotides amenable to antibody bioconjugation. You will propose and optimize novel synthetic and bioconjugation methods to support our fast-evolving antibody-oligonucleotide conjugate platform.  
• You will collaborate closely with cross-functions teams across medicinal chemistry and other departments to solve complex problems, including reaction optimization, assess synthetic feasibility, and propose novel ideas/concepts. 
• You will actively participate in discussions and present results in team meetings. 

Who You Are

• You are a team player with a strong background in medicinal/synthetic organic chemistry, capable of running reactions in parallel, and eager to explore new chemistry transformations. You love learning new technological skills and you are interested in improving process efficiencies. You are self-driven, well organized and a team player who can juggle multiple challenges in parallel to make impactful contributions to drug discovery.

Required Skills

• Ph.D. (1-3 years of experience[KG1.1]) or M.Sc (8+ years of experience) with strong chemistry background 
• Excellent knowledge of synthetic organic chemistry. Proficient in techniques related to synthesis, purification, and characterization of organic compounds. 
• Ability to independently design, plan, execute and interpret experiments. 
• Demonstrated track record of publications, and/or scientific presentations.
• Should be able to work in a multidisciplinary team.
• Excellent oral and written communication skills.
• Experience with antibody-drug conjugate or antibody-oligonucleotide conjugate drug discovery is a plus.
• Experience with bioconjugation chemistry is a plus.
• Familiarity with drug discovery in an industrial setting.

Compensation Details:

• Orbis Clinical is an equal opportunity employer that provides a reasonable range of compensation for our positions. Actual compensation is influenced by a wide array of factors including, but not limited to, skill set, level of experience and specific office location.
• The Pay Range for this position is $57.46 per hour, can vary depending on employment status.
• Orbis Clinical offers eligible employees health benefits (medical, dental, and vision), employer-paid basic life and AD&D insurance, and a partial employer match on a 401(k). 

EEO and Reasonable Accommodation Statement:

Epic Staffing Group is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, genetic information, veteran status, or any other characteristic protected by law. We also consider qualified applicants with criminal histories, consistent with applicable law. If you need assistance or an accommodation during the application process, please contact us.

 By applying for this position, you agree that any calls from Orbis Clinical and its subsidiaries may be monitored or recorded for training and quality assurance purposes.