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This position offers an exciting opportunity to be a key part of a research and development organization that is pioneering a new class of medicines. The Director, DMPK project representative, will provide direct support to multiple project teams across the discovery and early clinical development portfolio.
What you will be doing:
- Design and execute issue-driven ADME/PK studies to address critical discovery project needs, supporting program progression through lead optimization to early development
- Analyze and interpret preclinical ADME/PK data, communicating results and recommendations to project teams effectively
- Build and maintain strong collaborations with internal and external partners across chemistry, biology, pharmacology, CMC and other R&D disciplines
- Partner with discovery and clinical groups to design preclinical studies that inform clinical dosing strategy
- Contribute to key decisions including candidate selection, development strategy, and clinical trial design
- Author and review preclinical study reports, including nonclinical toxicology, DMPK and biomarker sections of regulatory documents
- Design and interpret PK/PD, efficacy and toxicology studies in collaboration with cross-functional teams
- Stay current with DMPK scientific literature and emerging technologies to identify potential applications for ongoing programs
- Help finalize clinical study protocols and reports with focus on DMPK aspects
Compensation Details:
- We provide a reasonable range of compensation for this position. Actual compensation is influenced by a wide array of factors including, but not limited to, skill set, level of experience and specific office location.
- The Pay Range for this position is $200k-$235k. It is possible that this position can be hired outside of this salary range based on experience.
EEO and Reasonable Accommodation Statement:
Orbis Clinical provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, housing, age, disability or genetics.
We will consider all qualified applicants for employment, including those with criminal histories, in a manner consistent with the requirements of applicable federal, state, and local laws.
By applying for this position, you agree that any calls from Orbis Clinical and its subsidiaries may be monitored or recorded for training and quality assurance purposes.
Fill out the form below to get in touch with our business development team, or call us at (781) 328-1132.
The Company is an equal opportunity employer and makes employment decisions on the basis of merit. The Company prohibits unlawful discrimination on the basis of race, color, national origin, ancestry, religion, creed, age, sex, sexual orientation, gender identity, pregnancy, marital status, physical or mental disability, medical condition or any other consideration made unlawful by federal, state or local laws. The Company will also provide reasonable accommodation to the known physical or mental disability of an otherwise qualified employee or applicant. Should you need any such accommodation, please contact the Company for further information. The Company is dedicated to ensuring that all decisions regarding personnel are in accordance with all applicable laws. I certify that all statements made in this application are true to the best of my knowledge. I understand that all falsification or misleading information given in my application may result in the termination of my employment with Orbis Clinical and its subsidiaries. Furthermore, I understand that my professional conduct and clinical performance is directly related to my ability to be placed on assignments for Orbis Clinical and that I will adhere to all regulations and guidelines of Orbis Clinical. I authorization Orbis Clinical to verify the information I have provided, to contact references, and to conduct criminal, education and personal background checks concerning my qualifications, and past employment record. I understand that nothing contained in this application is intended to create an employment contract, either verbal or written, with Orbis Clinical or its clients. Furthermore, I understand that my employment, it is “at will” and Orbis Clinical or I may terminate my employment at any time with or without notice and with or without case. I acknowledge that I will be legally obligated by the terms of this document by typing my name, which will constitute my signature, or manually signing, in the provided space and electronically transmitting this document to Orbis Clinical. I agree that Orbis Clinical and I may use electronic means to conduct this transaction and that this document shall be governed and construed by the laws of the State of Massachusetts.